通过扫描激光检眼镜在一名小口病患者中观察到的水尾现象。
Mizuo phenomenon observed by scanning laser ophthalmoscopy in a patient with Oguchi disease.
作者信息
Usui T, Ichibe M, Ueki S, Takagi M, Hasegawa S, Abe H, Sekiya K, Nakazawa M
机构信息
Department of Ophthalmology, Niigata University School of Medicine, Niigata, Japan.
出版信息
Am J Ophthalmol. 2000 Sep;130(3):359-61. doi: 10.1016/s0002-9394(00)00532-8.
PURPOSE
To elucidate the origin of the abnormal fundus reflex in Oguchi disease.
METHODS
The ocular fundus of a 63-year-old woman who showed a homozygous arrestin 1147delA mutation was observed by scanning laser ophthalmoscopy with the use of an argon blue laser (wavelength, 488 nm), a helium-neon laser (633 nm), and an infrared laser (780 nm).
RESULTS
Diffuse, fine, white particles, which do not exist in normal subjects, were clearly demonstrated only with the helium-neon laser. After 4-hour dark adaptation, the abnormal particles disappeared, but then they reappeared gradually during 30 minutes of light adaptation, in accordance with the golden metallic reflex.
CONCLUSION
The white particles found by helium-neon laser could be the origin of the abnormal fundus reflex in Oguchi disease.
目的
阐明小口病异常眼底反射的起源。
方法
使用氩蓝激光（波长488nm）、氦氖激光（633nm）和红外激光（780nm），通过扫描激光检眼镜观察一名显示纯合视 Arrestin 1147delA 突变的63岁女性的眼底。
结果
仅用氦氖激光能清晰显示出正常受试者不存在的弥漫性、细小白色颗粒。经过4小时暗适应后，异常颗粒消失，但在30分钟明适应期间又逐渐重新出现，与金色金属反射一致。
结论
氦氖激光发现的白色颗粒可能是小口病异常眼底反射的起源。
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