Hetzer F H, Baumann M, Röthlin M
Klinik für Viszeralchirurgie, Universitätsspital Zürich.
Praxis (Bern 1994). 2000 Aug 24;89(34):1317-21.
The anal fissure is one of the most frequent causes for anal pain. Conservative treatment usually consists of laxatives, local anesthetics and nitroglycerin cream. These therapies have a high recurrency rate. Surgical interventions, i.e. manual dilatation and sphincterotomy are fraught with the danger of fecal incontinence. The completely reversible effect of botulinum toxin injection opens new possibilities in the treatment of anal fissures. Its use is discussed as part of a 3-stage therapeutic regimen.
肛裂是引起肛门疼痛最常见的原因之一。保守治疗通常包括使用泻药、局部麻醉剂和硝酸甘油乳膏。这些治疗方法的复发率很高。手术干预,即手法扩张和括约肌切开术,存在大便失禁的风险。肉毒杆菌毒素注射具有完全可逆的效果,为肛裂治疗开辟了新的可能性。作为三阶段治疗方案的一部分,对其使用进行了讨论。