Schumacker K, Maerker-alzer G, Lukowski K J
Immun Infekt. 1975 Aug;3(4):182-7.
The course of viral hepatitis is markedly influenced by the immunologic response to the infective agent. The immune defense of viral diseases is specially connected to an intact function of T lymphocytes. Investigation of T cell function during acute and chronic viral hepatitis showed an altered immune response, recognizable from the relative number of T lymphocytes, the affinity and ability of lymphocytes to be stimulated by phytohemagglutinin and the demonstration of in vivo activated lymphocytes. Although the interpretation of some of these findings is still difficult, the study of the various cellular immune reactions permits a better understanding of the pathogenesis and course of viral hepatitis.
病毒性肝炎的病程受到对感染因子免疫反应的显著影响。病毒性疾病的免疫防御与T淋巴细胞的完整功能特别相关。对急性和慢性病毒性肝炎期间T细胞功能的研究表明，免疫反应发生了改变，这可从T淋巴细胞的相对数量、淋巴细胞被植物血凝素刺激的亲和力和能力以及体内活化淋巴细胞的表现中看出。尽管对其中一些发现的解释仍然困难，但对各种细胞免疫反应的研究有助于更好地理解病毒性肝炎的发病机制和病程。
