以结膜半月襞肿物形式出现的系统性淀粉样变性。
Systemic amyloidosis presenting as a mass of the conjunctival semilunar fold.
作者信息
Shields J A, Eagle R C, Shields C L, Green M, Singh A D
机构信息
Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
出版信息
Am J Ophthalmol. 2000 Oct;130(4):523-5. doi: 10.1016/s0002-9394(00)00567-5.
PURPOSE
To report a case of systemic amyloidosis that presented as a mass of the plica semilunaris (semilunar fold) of the conjunctiva.
METHODS
Case report.
RESULTS
A healthy 56-year-old man developed a fleshy, hemorrhagic lesion of the semilunar fold of the left conjunctiva. Excisional biopsy revealed an acellular lesion of the conjunctival stroma that stained positively for Congo red and showed apple-green birefringence and dichroism with polarization microscopy. The diagnosis was amyloidosis of the semilunar fold of the conjunctiva. Subsequent evaluation disclosed systemic amyloidosis. The patient remains asymptomatic.
CONCLUSIONS
Although conjunctival amyloidosis usually occurs as a localized lesion without systemic involvement, it can be the initial sign of systemic amyloidosis.
目的
报告1例表现为结膜半月襞肿块的系统性淀粉样变性病例。
方法
病例报告。
结果
一名56岁健康男性左侧结膜半月襞出现肉质、出血性病变。切除活检显示结膜基质无细胞病变，刚果红染色阳性，偏振显微镜下呈苹果绿双折射和二色性。诊断为结膜半月襞淀粉样变性。随后的评估发现存在系统性淀粉样变性。患者仍无症状。
结论
尽管结膜淀粉样变性通常表现为局限性病变，无全身受累，但它可能是系统性淀粉样变性的初始征象。
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