Tamai H, Tamai K, Yuasa H
Department of Ophthalmology, Koseiren Kamo Hospital, Toyota, Aichi, Japan.
Am J Ophthalmol. 2000 Oct;130(4):535-7. doi: 10.1016/s0002-9394(00)00566-3.
To report a case of pachymeningitis with pseudo-Foster Kennedy syndrome in a patient who was positive for perinuclear antineutrophil cytoplasmic antibody.
Case report. A 44-year-old man was examined for headache and diplopia.
Left eye showed limitation of abduction. Ocular fundus, computed tomography (CT), and magnetic resonance imaging (MRI) of the head and orbits were normal. The diplopia subsided spontaneously. Six months later, he noticed sudden visual loss in the left eye. The left eye showed optic disk atrophy and episcleritis, and the right eye showed papilloedema. Computed tomography and MRI exhibited thickened dura mater. Serum perinuclear antineutrophil cytoplasmic antibody level was highly increased.
Pachymeningitis with ocular involvement sometimes requires repeated CT or MRI for diagnosis. This disorder may be caused by microvasculitis.
报告1例核周型抗中性粒细胞胞浆抗体阳性患者伴假性福斯特·肯尼迪综合征的硬脑膜炎。
病例报告。一名44岁男性因头痛和复视接受检查。
左眼外展受限。眼部眼底、头部和眼眶的计算机断层扫描(CT)及磁共振成像(MRI)均正常。复视自行消退。6个月后,他注意到左眼突然视力丧失。左眼表现为视盘萎缩和巩膜外层炎,右眼表现为视乳头水肿。CT和MRI显示硬脑膜增厚。血清核周型抗中性粒细胞胞浆抗体水平显著升高。
累及眼部的硬脑膜炎有时需要重复进行CT或MRI检查以明确诊断。这种疾病可能由微血管炎引起。