[青霉素类抗生素对布鲁氏菌特性的影响]
[Effect of penicillin series antibiotics on the properties of Brucella].
作者信息
Kondrat'eva O V, Stepanov V M, Medvedenko N P
出版信息
Antibiotiki. 1979 Jun;24(6):454-8.
PMID:110251
Abstract
Investigation of the properties of antibiotic-resistant variants obtained experimentally from various species of Brucella indicated that benzylpenicillin, ampicillin and ceporin induced significant changes in the main properties of Brucella, i.e. phagolysability, agglutinability, production of brucellacin and hydrogen sulfate, attitude to dyes. Only the nutrient requirements of Brucella did not change when it was grown on synthetic media which is of great importance for investigation of changed Brucella strains.
摘要
对从各种布鲁氏菌物种中通过实验获得的抗生素抗性变体的特性进行研究表明，苄青霉素、氨苄青霉素和头孢菌素会使布鲁氏菌的主要特性发生显著变化，即吞噬溶解能力、凝集性、布鲁氏菌素和硫化氢的产生、对染料的反应。只有当布鲁氏菌在合成培养基上生长时，其营养需求才不会改变，这对于研究变化后的布鲁氏菌菌株非常重要。
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