Stothert J C, McBride L, Lewis J E, Danis R K, Barner H B
Ann Thorac Surg. 1979 Jul;28(1):54-9. doi: 10.1016/s0003-4975(10)63392-9.
One hundred twenty-nine infants with esophageal atresia and tracheoesophageal fistula were reviewed from 1955 to 1978. The overall mortality was 38%. Factors associated with the increased mortality include prematurity, pneumonia, and congenital defects other than this anomaly. A classification based on these factors in introduced, which provides the clinician with a prognostic survival rate greater than 90% with only physical examination, chest and abdominal roentgenography, and intravenous pyelography. Postoperative mortality was reduced to 11% in the last five years of the study; this is attributed to the exclusive use of the retropleural approach to the esophagus, more intensive postoperative ventilatory support, and routine use of parenteral nutrition.
回顾了1955年至1978年间129例患有食管闭锁和气管食管瘘的婴儿。总体死亡率为38%。与死亡率增加相关的因素包括早产、肺炎以及除此异常之外的先天性缺陷。引入了一种基于这些因素的分类方法,仅通过体格检查、胸部和腹部X线检查以及静脉肾盂造影,就能为临床医生提供大于90%的预后生存率。在研究的最后五年中,术后死亡率降至11%;这归因于食管仅采用胸膜后入路、术后更强化的通气支持以及肠外营养的常规使用。