Rabay-Chacar H, Rizkallah E, Hakimeh N I, Khoury L, Merhej M T
Pediatrics Department, St George Hospital (SGH), Beirut, Liban.
J Med Liban. 2000 Mar-Apr;48(2):108-11.
Mycoplasma pneumoniae (MP) is a frequent cause of respiratory tract infection. Extra-pulmonary manifestations may be neurological with variable expression, encephalitis being the most frequent. Meningitis, myelitis or polyradiculoneuritis are also reported. The pathophysiology of neurological manifestations remains poorly understood. Although not isolated from cerebral tissue, MP was reportedly detected in cerebro-spinal fluid (CSF) on several occasions. We report the case of a five-year-old girl who presented with fever, then pneumonia, and later developed spastic quadriparesis. MP was identified as the causative agent, evidenced by the presence of specific antibodies in both serum and CSF. The identification of a central nervous syndrome associated with confirmed MP infection extends the list of similar cases documented in individuals younger than 17 years of age.
肺炎支原体（MP）是呼吸道感染的常见病因。肺外表现可能为神经系统症状，表现多样，其中脑炎最为常见。也有脑膜炎、脊髓炎或多发性神经根神经炎的报道。神经系统表现的病理生理学仍知之甚少。尽管在脑组织中未分离出MP，但据报道在脑脊液（CSF）中多次检测到MP。我们报告了一名5岁女孩的病例，她先是发热，继而出现肺炎，后来发展为痉挛性四肢瘫。MP被确定为病原体，血清和脑脊液中均存在特异性抗体可证明这一点。与确诊的MP感染相关的中枢神经综合征的发现，扩展了17岁以下个体中记录的类似病例清单。
