Bakour S H, Khan K S, Gupta J K
Birmingham Minimal Access and Surgical Training, Centre Academic Department of Obstetrics and Gynaecology, University of Birmingham, UK.
BJOG. 2000 Oct;107(10):1312-4. doi: 10.1111/j.1471-0528.2000.tb11627.x.
We examined the relative significance of hysteroscopic and ultrasonographic evidence of endometrial atrophy in relation to insufficient sample on outpatient endometrial biopsy in women with abnormal uterine bleeding. Multivariate logistic regression modelling was used to evaluate the independent effects of age, menopausal status, hysteroscopic findings and sonographic endometrial thickness on outpatient endometrial sampling (sufficient or insufficient) used as the binary dependent variable. Insufficient sample on endometrial biopsy was associated with hysteroscopic finding of endometrial atrophy (OR 4.79, 95% CI 1.05-21.91, P = 0.04) and sonographic endometrial thickness below 5 mm (OR 0- 19. 95% CI 0.07-0.53, P = 0.001). There was no association with patient's age and menopausal status. In conclusion, when reassuring women with insufficient sample on outpatient endometrial biopsy, one can be confident about absence of pathology provided the hysteroscopic and sonographic endometrial assessment is consistent with endometrial atrophy.
我们研究了宫腔镜检查和超声检查显示的子宫内膜萎缩证据与异常子宫出血女性门诊子宫内膜活检样本不足之间的相对重要性。采用多变量逻辑回归模型，以门诊子宫内膜采样充足或不足作为二元因变量，评估年龄、绝经状态、宫腔镜检查结果及超声子宫内膜厚度的独立效应。子宫内膜活检样本不足与宫腔镜检查发现子宫内膜萎缩（比值比4.79，95%置信区间1.05 - 21.91，P = 0.04）及超声显示子宫内膜厚度小于5 mm（比值比0.19，95%置信区间0.07 - 0.53，P = 0.001）相关。与患者年龄和绝经状态无关。总之，当告知门诊子宫内膜活检样本不足的女性时，如果宫腔镜和超声对子宫内膜的评估与子宫内膜萎缩一致，那么可以确定不存在病变。
