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[犬猫自发性血液病的形态学分析]

[Morphological analysis of spontaneous hemoblastoses in dogs and cats].

作者信息

Khrustalev S A, Ponomar'kov V I, Khar'kovskaia N A

出版信息

Arkh Patol. 1979;41(5):23-30.

PMID:110293
Abstract

Information of the frequency and morphological characteristics of spontaneous hemoblastoses in dogs and cats observed in 1966-1978 are presented. Hemoblastoses were diagnosed in 90 dogs and 12 cats. Lymphoproliferative diseases were most frequent: lymphosarcomas (80 cases) and lymphocytic leukemias (11 cases). Ten dogs had mastocytomas and one--myeloid leukemia. The cell composition of the organs and tissues involved permitted to distinguish 3 cellular variants of lymphosarcoma: poorly differentiated, lymphoblastic, and prolymphocytic; in both species the poorly differentiated type of lymphosarcoma was predominant (47 cases). It is recommended to use spontaneous hemoblastoses of dogs and cats as an experimental model for investigations of the pathogenesis and therapy of human leukemias.

摘要

本文介绍了1966年至1978年间观察到的犬猫自发性血液病的发病频率及形态学特征。确诊患有血液病的犬有90只,猫有12只。淋巴增生性疾病最为常见:淋巴肉瘤(80例)和淋巴细胞白血病(11例)。10只犬患有肥大细胞瘤,1只患有髓性白血病。受累器官和组织的细胞组成可区分出淋巴肉瘤的3种细胞类型:低分化型、淋巴母细胞型和原淋巴细胞型;在两个物种中,低分化型淋巴肉瘤最为常见(47例)。建议将犬猫自发性血液病作为研究人类白血病发病机制和治疗方法的实验模型。

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