Molecular cloning of the cDNAs encoding the feline B-lymphocyte activation antigen B7-1 (CD80) and B7-2 (CD86) homologues which interact with human CTLA4-Ig.
作者信息
Nishimura Y, Shimojima M, Miyazawa T, Sato E, Nakamura K, Izumiya Y, Ikeda Y, Mikami T, Takahashi E
机构信息
Department of Veterinary Microbiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan.
出版信息
Eur J Immunogenet. 2000 Oct-Dec;27(5-6):427-30. doi: 10.1046/j.1365-2370.2000.00221.x.
Abstract
We cloned the cDNAs encoding the feline homologues of B-lymphocyte activation antigens B7-1 (CD80) and B7-2 (CD86). We expressed recombinant feline CD80 and CD86 molecules by the baculovirus expression system, and demonstrated their binding ability to human CTLA4-murine immunoglobulin fusion protein.
摘要
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