Yoden E, Hiratsuka J, Imajo Y, Yamamoto S, Kurebayashi J, Shimozuma K, Sonoo H
Department of Radiology, Kobe University School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku Kobe, Hyogo 650-0017, Japan.
Breast Cancer. 2000;7(3):252-5. doi: 10.1007/BF02967469.
We employed interstitial brachytherapy using a high dose rate Ir-192 remote afterloading unit in two breast cancer patients with locoregional recurrence. In the first case, skin metastasis was treated, with favorable control of the infield tumor but subsequent persistent sequelae and multiple outfield metastases. This experience caused us to be cautious when choosing brachytherapy for the second case, in whom a solitary metastasis to an axillary lymph node was successfully treated. Although this method is still investigational, it may play a critical role in the treatment of locoregional recurrence resistant to other treatment modalities.
我们对两名局部区域复发的乳腺癌患者采用高剂量率铱-192遥控后装装置进行组织间近距离放射治疗。在第一例中，对皮肤转移灶进行了治疗，内野肿瘤得到了良好控制，但随后出现了持续的后遗症和多个外野转移灶。这一经验使我们在为第二例患者选择近距离放射治疗时更加谨慎，该例患者腋窝淋巴结的孤立转移灶得到了成功治疗。尽管这种方法仍处于研究阶段，但它可能在对其他治疗方式耐药的局部区域复发的治疗中发挥关键作用。
