Ahmed S, Bierley R, Sheikh J I, Date E S
Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA.
Brain Inj. 2000 Sep;14(9):765-80. doi: 10.1080/026990500421886.
Post-traumatic amnesia (PTA) is a transient sequela of closed head injury (CHI). The term PTA has been in clinical use for over half a century, and generally refers to the subacute phase of recovery immediately after unconsciousness following CHI. The duration of PTA predicts functional outcome after CHI, but its pathophysiological mechanism is not known. This paper compares current methods of determining the duration of PTA, summarizes reports on neuropsychological deficits in PTA, reviews available data that allow inferences about its mechanism, and suggests methods for further exploration of its pathophysiology.
创伤后遗忘症（PTA）是闭合性颅脑损伤（CHI）的一种短暂后遗症。“PTA”这一术语已在临床使用了半个多世纪，通常指的是CHI后意识丧失后紧接着的亚急性恢复阶段。PTA的持续时间可预测CHI后的功能结局，但其病理生理机制尚不清楚。本文比较了当前确定PTA持续时间的方法，总结了关于PTA中神经心理学缺陷的报告，回顾了可用于推断其机制的现有数据，并提出了进一步探索其病理生理学的方法。
