Wilson J T, Teasdale G M, Hadley D M, Wiedmann K D, Lang D
Department of Psychology, University of Stirling, UK.
J Neurol Neurosurg Psychiatry. 1994 Feb;57(2):198-201. doi: 10.1136/jnnp.57.2.198.
Records of coma and post-traumatic amnesia (PTA) were collected for a group of 38 patients with closed head injury. The results confirmed earlier studies indicating that patients may have short or negligible coma but report prolonged PTA. Comparison of eight patients with prolonged PTA (> 7 days) and short coma (< 6 hours) with the rest of the group on MRI in the acute stage showed that these patients had significantly more extensive hemispheric damage. In the group as a whole both coma and PTA were related to the number of areas in central brain structures in which lesions were detected, but only PTA was significantly related to the number of hemispheric areas in which lesions were found. It is concluded that although both coma and PTA are related to brain damage they reflect disparate patterns of lesions. Assessment of PTA can thus provide additional information concerning severity of injury.
收集了38例闭合性颅脑损伤患者的昏迷和创伤后遗忘（PTA）记录。结果证实了早期研究，表明患者可能有短暂或可忽略不计的昏迷，但报告有延长的PTA。在急性期，对8例PTA延长（>7天）且昏迷短暂（<6小时）的患者与该组其他患者进行MRI比较，结果显示这些患者的半球损伤明显更广泛。在整个组中，昏迷和PTA均与检测到病变的脑中央结构区域数量有关，但只有PTA与发现病变的半球区域数量显著相关。得出的结论是，虽然昏迷和PTA都与脑损伤有关，但它们反映了不同的损伤模式。因此，对PTA的评估可以提供有关损伤严重程度的额外信息。
