Nakanishi F, Takahashi H, Ohara K
Department of Ophthalmology, Nippon Medical School, Tokyo, Japan.
Jpn J Ophthalmol. 2000 Sep-Oct;44(5):561-4. doi: 10.1016/s0021-5155(00)00207-0.
A case report of contralateral acute retinal necrosis (ARN) following herpes zoster ophthalmicus.
A 61-year-old male patient developed iridocyclitis and well-demarcated creamy-white retinal lesions at the nasal periphery in the right eye 1 month after herpes zoster ophthalmicus in the left eye. The patient had undergone surgery for primary lung cancer, and had subsequent intracranial metastasis of the tumor.
The clinical diagnosis of ARN was supported by polymerase chain reaction investigation of the aqueous humor resulting in positive for varicella-zoster virus. Retinal lesions disappeared after systemic treatment with acyclovir, corticosteroids, and acetylsalicylate. No retinal detachment developed.
We propose a careful ophthalmic follow-up for herpes zoster ophthalmicus patients because of the possibility of acute retinal necrosis developing in the contralateral eye.
1例眼部带状疱疹后发生对侧急性视网膜坏死(ARN)的病例报告。
一名61岁男性患者,左眼发生眼部带状疱疹1个月后,右眼出现虹膜睫状体炎,鼻侧周边视网膜出现界限清晰的乳白色病变。该患者曾接受原发性肺癌手术,随后肿瘤发生颅内转移。
房水聚合酶链反应检测结果显示水痘-带状疱疹病毒呈阳性,支持ARN的临床诊断。经阿昔洛韦、皮质类固醇和乙酰水杨酸全身治疗后,视网膜病变消失。未发生视网膜脱离。
由于眼部带状疱疹患者对侧眼有发生急性视网膜坏死的可能,我们建议对其进行仔细的眼科随访。