Andrew M J, Baker R A, Kneebone A C, Knight J L
Cardiac Surgical Research Group, Department of Medicine, Flinders Medical Centre and Flinders University of South Australia, Bedford Park, South Australia 5042, Adelaide, Australia.
J Psychosom Res. 2000 Jun;48(6):537-46. doi: 10.1016/s0022-3999(00)00089-1.
mood disorders and neuropsychological deficits are both commonly reported occurrences after cardiac surgery. We examined the relationship between mood state and postoperative cognitive deficits in this population.
assessments of neuropsychological functions and mood state (depression, anxiety, stress scales; DASS) were performed preoperatively and postoperatively on 147 patients undergoing cardiac surgery.
the incidence of preoperative depression, anxiety, and stress symptomatology was 16%, 27%, and 16%, respectively. The incidence of postoperative anxiety symptomatology significantly increased to 45% (p<0.001), while the incidence of depression and stress symptomatology remained stable (19% and 15%, respectively; ns). Changes in mood state did not influence changes in neuropsychological performance. Preoperative mood was a strong predictor of postoperative mood, and was related to postoperative deficits on measures of attention and memory.
an assessment of preoperative mood is critical in identifying patients at risk of postoperative mood disorders and neuropsychological deficits. Measures assessing somatic manifestations of anxiety may not be suitable for a surgical population.
情绪障碍和神经心理缺陷都是心脏手术后常见的情况。我们研究了该人群中情绪状态与术后认知缺陷之间的关系。
对147例接受心脏手术的患者在术前和术后进行神经心理功能和情绪状态（抑郁、焦虑、压力量表；DASS）评估。
术前抑郁、焦虑和压力症状的发生率分别为16%、27%和16%。术后焦虑症状的发生率显著增加至45%（p<0.001），而抑郁和压力症状的发生率保持稳定（分别为19%和15%；无统计学意义）。情绪状态的变化并未影响神经心理表现的变化。术前情绪是术后情绪的有力预测指标，且与术后注意力和记忆力测量指标的缺陷有关。
术前情绪评估对于识别有术后情绪障碍和神经心理缺陷风险的患者至关重要。评估焦虑躯体表现的措施可能不适用于手术人群。
