[基因治疗中的逆转录病毒载体]
[Retroviral vectors in gene therapy].
作者信息
Prasolov V S, Ivanov D S
机构信息
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow.
出版信息
Vopr Med Khim. 2000 May-Jun;46(3):207-25.
PMID:11033882
Abstract
This review describes the systems of retroviral transfer and expression of the genes that are widely applied in basic biological research and in gene therapy. Unique features of retroviruses providing a background for construction of retroviral vectors and the methods to use these vectors are discussed.
摘要
本综述描述了逆转录病毒基因转移和表达系统，这些系统广泛应用于基础生物学研究和基因治疗。文中讨论了逆转录病毒的独特特性，这些特性为构建逆转录病毒载体提供了背景知识，还讨论了使用这些载体的方法。
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