van Valkengoed I G, Boeke A J, Morré S A, van den Brule A J, Meijer C J, Devillé W, Bouter L M
Institute for Research in Extramural Medicine, Vrije Universiteit, Amsterdam, The Netherlands.
Sex Transm Dis. 2000 Oct;27(9):504-7. doi: 10.1097/00007435-200010000-00003.
In an inner-city population with a low prevalence of Chlamydia trachomatis infection, selective screening may be indicated to increase the efficiency of screening.
To evaluate the performance of sets of selective screening criteria for asymptomatic Chlamydia trachomatis infection in an inner-city population. The criteria were derived from reports of studies carried out in various settings.
A total of 5714 women age 15 to 40 years living in Amsterdam were invited for a screening based on home-obtained urine specimens. Criteria identified from the literature were applied to the screening population. A calculated area under the receiver-operator characteristic curve (AUC) of greater than 0.75 was considered a good measure of diagnostic accuracy.
Of the four sets of criteria, selection based on the following determinants showed the highest diagnostic accuracy: younger than 25 years, being unmarried, number of partners during the previous 6 months, Surinam or Antillean origin (black), and vaginal douching (AUC, 0.67; 95% CI, 0.65-0.69). Selection based on age alone showed an AUC of 0.57 (95% CI, 0.55-0.69).
The performance of selective screening criteria for asymptomatic C trachomatis infection in an inner-city population in Amsterdam was insufficient to recommend its implementation in practice.
在沙眼衣原体感染患病率较低的市中心人群中，可能需要进行选择性筛查以提高筛查效率。
评估针对市中心人群无症状沙眼衣原体感染的一系列选择性筛查标准的性能。这些标准源自不同环境下开展的研究报告。
共邀请了5714名年龄在15至40岁、居住在阿姆斯特丹的女性，基于在家采集的尿液标本进行筛查。将从文献中确定的标准应用于筛查人群。计算得出的受试者工作特征曲线下面积（AUC）大于0.75被认为是诊断准确性的良好指标。
在四套标准中，基于以下决定因素进行选择显示出最高的诊断准确性：年龄小于25岁、未婚、过去6个月的性伴侣数量、苏里南或安的列斯群岛血统（黑人）以及阴道灌洗（AUC，0.67；95%可信区间，0.65 - 0.69）。仅基于年龄进行选择的AUC为0.57（95%可信区间，0.55 - 0.69）。
在阿姆斯特丹市中心人群中，针对无症状沙眼衣原体感染的选择性筛查标准的性能不足以推荐在实际中实施。
