Cowell S F, Egan G F, Code C, Harasty J, Watson J D
School of Communication Sciences and Disorders, University of Sydney, NSW 2006, Australia.
Neuroimage. 2000 Nov;12(5):565-73. doi: 10.1006/nimg.2000.0640.
We examined cerebral activation patterns with positron emission tomography (PET) in 12 right-handed normal volunteers while they were completing simple calculation tasks or merely repeating numbers. Using a parametric experimental design, during calculation we found activation in the medial frontal/cingulate gyri, left dorsolateral prefrontal cortex, left anterior insular cortex and right anterior insular cortex/putamen, left lateral parietal cortex, and the medial thalamus. Number repetition engaged bilateral inferior sensorimotor cortex, bilateral temporal areas, and left inferior frontal cortex. These results suggest a functional anatomical network for simple calculation, which includes aspects of attention, auditory, and motor processing and the phonological store and articulatory loop components of working memory; they add some support for a special role of the parietal cortex in calculation tasks.
我们使用正电子发射断层扫描（PET）对12名右利手正常志愿者在完成简单计算任务或仅仅重复数字时的大脑激活模式进行了研究。采用参数实验设计，在计算过程中，我们发现内侧额叶/扣带回、左侧背外侧前额叶皮质、左侧前岛叶皮质和右侧前岛叶皮质/壳核、左侧顶叶外侧皮质以及内侧丘脑有激活。数字重复激活了双侧下感觉运动皮质、双侧颞叶区域以及左侧额下皮质。这些结果表明存在一个用于简单计算的功能解剖网络，其中包括注意力、听觉和运动处理方面以及工作记忆的语音存储和发音环路成分；它们为顶叶皮质在计算任务中的特殊作用提供了一些支持。
