Schworm H D, Boergen K P
Department of Ophthalmology, Ludwig Maximilians University, Munich, Germany.
Strabismus. 2000 Sep;8(3):179-85.
A prospective study on the saccadic properties of 10 patients with acute Graves' ophthalmopathy (GO) compared to 10 healthy individuals was performed using the induction scleral search coil. No significant changes were observed among six patients with moderate disease. In four patients suffering from optic nerve compression, however, a substantial decrease of saccadic velocity and related parameters was detected. The absence of saccadic changes in earlier moderate stages of GO seems to be based on adaptation of the central saccadic generator. The velocity reduction in connection with a marked elevation of intraorbital pressure could be indicative of paretic motoneuron disturbances.
一项前瞻性研究利用感应巩膜搜索线圈对10例急性格雷夫斯眼病（GO）患者与10名健康个体的眼球运动特性进行了比较。6例中度疾病患者未观察到显著变化。然而，在4例患有视神经压迫的患者中，检测到眼球运动速度及相关参数大幅下降。GO早期中度阶段未出现眼球运动变化似乎是基于中枢眼球运动发生器的适应性。与眶内压显著升高相关的速度降低可能表明运动神经元麻痹性紊乱。
