Roudenok V
Department of Human Anatomy, Minsk State Medical Institute, Belarus.
Ann Anat. 2000 Sep;182(5):465-9. doi: 10.1016/S0940-9602(00)80059-X.
The distribution of calcitonin gene-related peptide-immunoreactivity (CGRP-IR) in human neonatal paravertebral ganglia was demonstrated by the method of indirect immunohistochemistry. A marked population (up to 21%) of CGRP-IR neurons and varicose nerve fibres was observed. The number of calcionin gene-related peptide-immunoreactive neurons varied from ganglion to ganglion in the sympathetic trunk. In addition to its cotransmitter functions, the existence of CGRP in neonatal ganglionic nerve cells was suggested by its inductive and trophic actions on the growth and differentiation of neurons.
采用间接免疫组织化学方法，证实了降钙素基因相关肽免疫反应性（CGRP-IR）在人新生儿椎旁神经节中的分布情况。观察到大量（高达21%）的CGRP-IR神经元和曲张神经纤维。交感干中降钙素基因相关肽免疫反应性神经元的数量在不同神经节之间存在差异。除了其共递质功能外，新生儿神经节神经细胞中CGRP的存在还因其对神经元生长和分化的诱导及营养作用而得到提示。
