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Beta-lactamase production by oral anaerobic gram-negative species in infants in relation to previous antimicrobial therapy.婴儿口腔厌氧革兰氏阴性菌产生β-内酰胺酶与既往抗菌治疗的关系。
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The effect of chemotherapy on the supragingival plaque of pediatric cancer patients.化疗对儿科癌症患者龈上菌斑的影响。
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Bacteremia by multidrug-resistant Capnocytophaga sputigena.多重耐药的生痰二氧化碳嗜纤维菌引起的菌血症
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In vitro activity of beta-lactamase inhibitors against clinical isolates of Acinetobacter species.
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Septicemia caused by Capnocytophaga in a granulocytopenic patient with glossitis.一名粒细胞减少且患有舌炎的患者因二氧化碳嗜纤维菌感染引发败血症。
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Antimicrobial susceptibility of Capnocytophaga.二氧化碳嗜纤维菌的抗菌药敏性。
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Enzymatic characterization of some oral and nonoral gram-negative bacteria with the API ZYM system.使用API ZYM系统对一些口腔和非口腔革兰氏阴性菌进行酶学特性分析。
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二氧化碳嗜纤维菌分离株对β-内酰胺类抗生素和β-内酰胺酶抑制剂的体外敏感性

In vitro susceptibilities of Capnocytophaga isolates to beta-lactam antibiotics and beta-lactamase inhibitors.

作者信息

Jolivet-Gougeon A, Buffet A, Dupuy C, Sixou J L, Bonnaure-Mallet M, David S, Cormier M

机构信息

Laboratoire de Microbiologie Pharmaceutique, UPRES-EA 1254, Université de Rennes I, 35000 Rennes, France.

出版信息

Antimicrob Agents Chemother. 2000 Nov;44(11):3186-8. doi: 10.1128/AAC.44.11.3186-3188.2000.

DOI:10.1128/AAC.44.11.3186-3188.2000
PMID:11036049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC101629/
Abstract

The susceptibilities of 43 pharyngeal isolates of Capnocytophaga to beta-lactam antibiotics, alone or in combination with beta-lactamase inhibitors, were tested by an agar dilution method. The 34 beta-lactamase-positive strains were highly resistant to beta-lactams, but the intrinsic activities of clavulanate, tazobactam, and sulbactam against Capnocytophaga, even beta-lactamase producers, indicates that these beta-lactamase inhibitors could be used for empirical treatment of neutropenic patients with oral sources of infection.

摘要

采用琼脂稀释法检测了43株咽峡炎二氧化碳嗜纤维菌分离株对β-内酰胺类抗生素单独或与β-内酰胺酶抑制剂联合使用时的敏感性。34株β-内酰胺酶阳性菌株对β-内酰胺类高度耐药，但克拉维酸、他唑巴坦和舒巴坦对二氧化碳嗜纤维菌（即使是产β-内酰胺酶的菌株）的固有活性表明，这些β-内酰胺酶抑制剂可用于经验性治疗有口腔感染源的中性粒细胞减少患者。