Kikuchi-Yorioka Y, Sawaguchi T
Department of Psychology, Hokkaido University, N10 W7, Kita-ku, Sapporo 060-0810, Japan.
Nat Neurosci. 2000 Nov;3(11):1075-6. doi: 10.1038/80581.
The dorsolateral area of the prefrontal cortex (PFC) in primates is involved in visuospatial working memory, but the cellular basis of spatial working memory for auditory information is poorly understood. Here we examined dorsolateral PFC neurons using visual and auditory oculomotor delayed-response tasks. We found that the dorsolateral PFC contains two groups of neurons, each showing directional delay-period activity depending on the location of the visual or auditory cue, suggesting that parallel neuronal processes for visual and auditory spatial working memory occur in the dorsolateral PFC.
灵长类动物前额叶皮质（PFC）的背外侧区域参与视觉空间工作记忆，但对于听觉信息的空间工作记忆的细胞基础却知之甚少。在这里，我们使用视觉和听觉动眼延迟反应任务来研究背外侧PFC神经元。我们发现，背外侧PFC包含两组神经元，每组神经元根据视觉或听觉线索的位置表现出方向延迟期活动，这表明视觉和听觉空间工作记忆的平行神经元过程发生在背外侧PFC中。
