一种用于评估滑膜关节局部应用的关节内方法。
An intra-articular method for assessing topical application to a synovial joint.
作者信息
Holland T, Jones R, Basford A, Child T, Smith A
机构信息
Covance Laboratories Limited, Harrogate, UK.
出版信息
Lab Anim. 2000 Jul;34(3):298-300. doi: 10.1258/002367700780384654.
PMID:11037124
Abstract
Intra-articular injection of drugs is increasingly used in human medicines. We report a method for the direct administration of a test substance to the synovial fluid of the canine stifle joint. This method caused little distress or pathology, making it suitable for pre-clinical assessment of new drugs in dogs and other species.
摘要
关节内注射药物在人类医学中的应用越来越广泛。我们报告了一种将测试物质直接注入犬膝关节滑液的方法。该方法几乎不会引起疼痛或病理变化，适用于对犬类及其他物种的新药进行临床前评估。
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