Mills S A, Seigler H F, Wolfe W G
Ann Surg. 1975 Nov;182(5):617-26. doi: 10.1097/00000658-197511000-00014.
A retrospective analysis of 193 renal transplant recipients yielded 15 patients who developed pulmonary mycosis posttransplantation and one case in which mycotic lung infection existed at the time of transplant surgery. Agent responsible for infection included Nocardia asteroides in 8 cases, Asperigillus flavus in 5 cases, Cryptococcus neoformans in 4 patients and Candida albicans in 2 cases. Two cases had mixed mycotic infections. Ten patients died, of which 7 had diagnosis established antemortem. Two cases had diagnosis established by thoracotomy and 1 case by transtracheal aspiration. Problems in establishing accurate diagnosis are discussed with emphasis placed on the need for more frequent use of transtracheal aspiration and thoracotomy for precise diagnosis.
对193例肾移植受者进行回顾性分析，发现15例在移植后发生肺部真菌病，1例在移植手术时即存在肺部真菌感染。感染病原体包括8例星形诺卡菌、5例黄曲霉、4例新型隐球菌和2例白色念珠菌。2例为混合真菌感染。10例患者死亡，其中7例生前确诊。2例经开胸手术确诊，1例经经气管吸引确诊。文中讨论了准确诊断存在的问题，强调需要更频繁地使用经气管吸引和开胸手术以进行精确诊断。
