[儿童腹膜后神经节细胞瘤]
[Retroperitoneal ganglioneuroma in childhood].
作者信息
Vara Castrodeza A, Madrigal Rubiales B, Pérez del Río M J, García Hernández J B, Ablanedo Ablanedo P
机构信息
Servicio de Radiología, Hospital Na Sa Covadonga, Oviedo, Asturias, España.
出版信息
Arch Esp Urol. 2000 Sep;53(7):648-51.
OBJECTIVE
An incidentally discovered retroperitoneal ganglioneuroma in a 4-year-old child is presented.
METHODS
Ultrasonography and CT were performed. The surgical specimen was analyzed by macroscopic, histological and immunohistochemical techniques.
RESULTS
US and CT localized a retroperitoneal mass independent from the left kidney and adrenal gland. The histological study showed a fascicular proliferation with myxoid and fibrillar areas mixed with mature ganglion cells. These cells were positive for neurofilament and neuron specific enolase. The patient had a favorable outcome with no signs of tumor recurrence.
CONCLUSIONS
Ganglioneuroma is a rare, completely mature tumor that has to be differentiated from neuroblastoma.
目的
报告一例4岁儿童偶然发现的腹膜后神经节细胞瘤。
方法
进行了超声检查和CT检查。手术标本采用大体、组织学和免疫组化技术进行分析。
结果
超声和CT定位了一个独立于左肾和肾上腺的腹膜后肿块。组织学研究显示有束状增生，伴有黏液样和纤维状区域，混有成熟的神经节细胞。这些细胞神经丝和神经元特异性烯醇化酶呈阳性。患者预后良好，无肿瘤复发迹象。
结论
神经节细胞瘤是一种罕见的、完全成熟的肿瘤，必须与神经母细胞瘤相鉴别。
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