Ryska A, Kucera M
Fingerlandův ústav patologie, Fakultní nemocnice, Hradec Králové.
Cesk Patol. 1999 Apr;35(2):67-71.
A case of a cystic metastasis of squamous cell carcinoma of palatine tonsil in a 54-year-old male is reported, clinically presenting as a branchiogenic cyst. The grade of differentiation of the squamous cell epithelium lining the cyst was very variable: in some areas it was extremely well differentiated, thus resembling common benign branchial cleft cyst; transition to dysplastic areas with features of carcinoma in situ was visible and finally, in one small focus, invasion of the epithelial structures into the lymphoid tissue was observed. Despite its metastatic nature, the tumor fulfilled histological criteria of a so called malignant branchiogenic cyst (branchiogenic carcinoma). The authors discuss the existence of primary malignant branchiogenic cyst and the criteria necessary for its diagnosis.
报告了一例54岁男性腭扁桃体鳞状细胞癌囊性转移病例，临床上表现为鳃裂囊肿。囊肿内衬的鳞状上皮分化程度差异很大：在某些区域分化极好，类似于常见的良性鳃裂囊肿；可见向具有原位癌特征的发育异常区域转变，最终在一个小区域观察到上皮结构侵入淋巴组织。尽管该肿瘤具有转移性，但符合所谓恶性鳃裂囊肿（鳃裂癌）的组织学标准。作者讨论了原发性恶性鳃裂囊肿的存在及其诊断所需的标准。
