Pan B S
Zhongshan Hospital, Shanghai Medical University.
Sheng Li Ke Xue Jin Zhan. 1997 Apr;28(2):101-7.
The term "neurosteroids" applies to those steroids that are synthesized in nervous system independent of supply by peripheral endocrine glands. The neurosteroids biosynthetic pathway, the mechanisms of neurosteroids in regulating neuronal activities and the neuromodulatory effects of neurosteroids, particularly the bimodal regulation of GABAA receptors, have been reported.
术语“神经甾体”适用于那些在神经系统中合成、独立于外周内分泌腺供应的甾体。神经甾体的生物合成途径、神经甾体调节神经元活动的机制以及神经甾体的神经调节作用,特别是对GABAA受体的双峰调节,均已有报道。