酿酒酵母核DNA和线粒体DNA中紫外线诱导的嘧啶二聚体在各种辐照后处理下的命运及其对存活率和细胞质“小菌落”诱导的影响。
The fate of UV-induced pyrimidine dimers in the nuclear and mitochondrial DNAs of Saccharomyces cerevisiae on various postirradiation treatments and its influence on survival and cytoplasmic "petite" induction.
作者信息
Waters R, Moustacchi E
出版信息
Basic Life Sci. 1975;5B:557-65. doi: 10.1007/978-1-4684-2898-8_21.
PMID:1103872
Abstract
The photoreactivability of UV-induced pyrimidine dimers in the nuclear and mitochondrial DNAs of Saccharomyces cerevisiae has been investigated in conjunction with the fate of these photoproducts following postirradiation dark incubation in saline and nutrient media. In all instances, survival and "petite" induction were measured. An attempt has been made to relate these results to present ideas on the repair of UV damages in DNA.
摘要
结合紫外线照射后在盐溶液和营养培养基中黑暗孵育时光产物的命运，研究了酿酒酵母核DNA和线粒体DNA中紫外线诱导的嘧啶二聚体的光复活能力。在所有情况下，都测量了存活率和“小菌落”诱导率。已尝试将这些结果与目前关于DNA中紫外线损伤修复的观点联系起来。
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