Wang S, Zhang Y, Zou W
Department of Nephrology, First Hospital Beijing Medical University, Beijing.
Zhonghua Yi Xue Za Zhi. 1998 Oct;78(10):782-4.
To evaluate the use of electron microscopy(EM) in pathological diagnosis of renal biopsies.
777 cases of renal biopsy in Department of Nephrology, First Hospital of Beijing Medical University from Jan 1995 to Jun 1997 were studied. We compared the preliminary diagnosis by light microscopy(LM) and immuno-fluorescence(IF) with the final diagnosis by electron microscopy(EM). The use of EM in the diagnosis was divided into three parts. EM was needed to make a correct final diagnosis, provided confirmatory data or additional information relevant to the diagnosis and was complementary to LM and IF.
Among 777 cases of renal biopsy, EM was needed to make a correct final diagnosis in 18.5%, and provided important referential information in 13.5%.
EM provided useful diagnostic information in about one third cases of renal biopsy.
评估电子显微镜（EM）在肾活检病理诊断中的应用。
研究了1995年1月至1997年6月北京医科大学第一医院肾内科的777例肾活检病例。我们将光镜（LM）和免疫荧光（IF）的初步诊断与电子显微镜（EM）的最终诊断进行了比较。EM在诊断中的应用分为三个部分。EM对于做出正确的最终诊断是必要的，可提供与诊断相关的确证数据或额外信息，并且是对LM和IF的补充。
在777例肾活检病例中，18.5%的病例需要EM做出正确的最终诊断，13.5%的病例提供了重要的参考信息。
EM在约三分之一的肾活检病例中提供了有用的诊断信息。
