Domon M, Kurabayashi T, Shiga Y
Department of Dental Radiology, Tokyo Medical and Dental University, Japan.
J Dent Res. 1988 Jan;67(1):37-43. doi: 10.1177/00220345880670010701.
In order to correlate pathological changes of mouse parotid glands with their sialographic images, we conducted studies on mice with known pathological changes: mice with Stensen's duct ligated, NZB mice with a systemic auto-immune disease, and aged mice. The sialographic images were found to be specific for the pathological changes: The glands after ligation of Stensen's duct were characterized by dilated, large excretory ducts with a reduced system of peripheral ducts; the glands of NZB mice showed lobular leakage of the contrast medium from small excretory ducts; and the glands of aged mice showed a great reduction in the ductal system. It is concluded that sialography yields useful information on the pathological changes of the ductal systems in the mouse parotid gland.
为了将小鼠腮腺的病理变化与其涎腺造影图像相关联，我们对具有已知病理变化的小鼠进行了研究：结扎了斯滕森氏管的小鼠、患有全身性自身免疫疾病的新西兰黑小鼠（NZB小鼠）以及老年小鼠。结果发现涎腺造影图像对于病理变化具有特异性：结扎斯滕森氏管后的腺体特征为排泄管扩张、粗大，周边导管系统减少；NZB小鼠的腺体显示造影剂从小排泄管呈小叶状渗漏；老年小鼠的腺体则显示导管系统大幅减少。得出的结论是，涎腺造影可提供有关小鼠腮腺导管系统病理变化的有用信息。
