Sharma P, Tandon R, Kumar S, Anand S
Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, and the Department of Biomedical Engineering, Indian Institute of Technology, New Delhi, India.
J AAPOS. 2000 Oct;4(5):287-90. doi: 10.1067/mpa.2000.107900.
Treatment options for congenital nystagmus without null position are limited. The purpose of this study was to evaluate the role of auditory biofeedback in controlling congenital nystagmus.
Ten patients with congenital nystagmus without null position underwent 6 sessions (twice a week for 3 weeks) of auditory biofeedback. Each half-hour session had simultaneous electronystagmographic recording done during the session.
The patients could reduce the nystagmus during the treatment sessions. Mean amplitude (degrees) of nystagmus was reduced from 6. 28 +/- 4.94 to 3.05 +/- 2.48 (P =.028) and mean intensity (amplitude x frequency) was reduced from 33.37 +/- 22.84 to 13.35 +/- 7.99 (P =. 0174), but the mean frequency change was not significant, from 5.8 +/- 1.05 to 4.98 +/- 1.35 (P =.148). The mean amplitude and mean intensity decreased by 51% and 60%, respectively. After completion of the session, although a subjective improvement was reported, the patient's binocular visual acuity on Snellen's charts and contrast sensitivity did not show any significant change. Also no sustained benefit was noted because the electronystagmographic recordings reverted to baseline after the auditory stimulus for biofeedback was discontinued.
Simultaneous electronystagmographic recording shows significant reduction of nystagmus amplitude and intensity because of auditory biofeedback only during the treatment session. The beneficial effect does not persist after the auditory stimulus is discontinued. No objective effect on visual acuity and contrast sensitivity was noted after the therapy.
对于无静止眼位的先天性眼球震颤,其治疗选择有限。本研究旨在评估听觉生物反馈在控制先天性眼球震颤中的作用。
10例无静止眼位的先天性眼球震颤患者接受了6次(每周2次,共3周)听觉生物反馈治疗。每次半小时的治疗过程中同时进行眼震电图记录。
患者在治疗过程中能够减少眼球震颤。眼球震颤的平均幅度(度)从6.28±4.94降至3.05±2.48(P = 0.028),平均强度(幅度×频率)从33.37±22.84降至13.35±7.99(P = 0.0174),但平均频率变化不显著,从5.8±1.05降至4.98±1.35(P = 0.148)。平均幅度和平均强度分别下降了51%和60%。治疗结束后,尽管患者报告有主观改善,但在斯内伦视力表上的双眼视力和对比敏感度均未显示出任何显著变化。此外,未观察到持续的益处,因为在停止用于生物反馈的听觉刺激后,眼震电图记录恢复到了基线水平。
同步眼震电图记录显示,仅在治疗过程中,由于听觉生物反馈,眼球震颤的幅度和强度显著降低。听觉刺激停止后,有益效果不再持续。治疗后未观察到对视力和对比敏感度的客观影响。