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伴有急性肾衰竭的HELLP综合征中系膜增生性肾小球肾炎的不典型表现。

Unusual presentation of mesangial proliferative glomerulonephritis in HELLP syndrome associated with acute renal failure.

作者信息

Fang J T, Chen Y C, Huang C C

机构信息

Department of Nephrology, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan.

出版信息

Ren Fail. 2000;22(5):641-6. doi: 10.1081/jdi-100100905.

Abstract

Acute renal failure in pregnancy is not common in industrialized countries. HELLP syndrome (hemolysis, elevated liver enzyme, and low platelets) was one of the causes of acute renal failure in pregnancy, but renal pathological findings in case of acute renal failure had rarely been reported. We reported an unusual case of HELLP syndrome with acute renal failure requiring renal replacement therapy and which histopathologic findings of kidney biopsy showed mesangial proliferative glomerulonephritis and her renal function completely recovered after immediate artificial abortion, supportive management, transfusion of blood products, and hemodialysis.

摘要

在工业化国家,妊娠期急性肾衰竭并不常见。HELLP综合征(溶血、肝酶升高和血小板减少)是妊娠期急性肾衰竭的病因之一,但急性肾衰竭时的肾脏病理表现鲜有报道。我们报告了一例罕见的HELLP综合征合并急性肾衰竭病例,该患者需要肾脏替代治疗,肾活检的组织病理学结果显示为系膜增生性肾小球肾炎。在立即进行人工流产、支持治疗、输注血液制品和血液透析后,患者的肾功能完全恢复。

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