Buchatskii A G, Kazachenko K Y, Alexandrov A A
Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182, Russia.
Biochemistry (Mosc). 2000 Sep;65(9):1019-22.
Significant identity between a hypothetical 92.3-kD human protein and angiotensin-converting enzyme (ACE; peptidyl-dipeptidase A; kininase II) has been found. Certain specific regions of the 92.3-kD protein indicate that this unidentified molecule may be a member of the zinc metalloprotease family. A method is suggested for determination of a structural and functional family of proteins with unknown structure and function.