Contart P, Baruffi R L, Coelho J, Mauri A L, Petersen C, Franco Júnior J G
Center for Human Reproduction, Sinhá Junqueira Maternity Foundation, Rua D. Alberto Gonçalves, Ribeirão Preto, SP, Brazil.
J Assist Reprod Genet. 2000 Jul;17(6):329-34. doi: 10.1023/a:1009405128160.
The objective of the present study was to evaluate power Doppler of the endometrium as a parameter for the prognosis of embryo implantation in patients who underwent intracytoplasmic sperm injection (ICSI).
The power Doppler was performed on a transverse section at the level of the uterine fundus on the day of human chorionic gonadotropin in 185 patients who submitted to ovarian stimulation for ICSI. The endometrium was divided into four equal quadrants and classified as grade I, II, III, or IV according to the visualization of the power Doppler in the quadrants. The color Doppler signal was considered to be positive when it reached at least the basal layer of the endometrium.
Age, number of days of stimulation, number of follicles > or = 16 mm, number of oocytes in metaphase II retrieved, and fertilization rate did not differ patients with the four different types of endometrial grades. Endometrial thickness and the pulsatility index of uterine artery also were similar for the four grades. The rate of embryo implantation also did not differ significantly (P = 0.53) among groups: grade I = 10%; grade II = 11.6%; grade III = 15.4%; grade IV = 10.5%. The pregnancy rates were grade I = 25%; grade II = 29.7%; grade III = 37.5%; grade IV = 23.8% (P = 0.44).
Our data demonstrate that isolated evaluation of endometrial vascularization with power Doppler is not an important factor for the prediction of pregnancy in an ICSI program.
本研究的目的是评估子宫内膜的能量多普勒作为接受卵胞浆内单精子注射（ICSI）患者胚胎着床预后的一个参数。
对185例接受ICSI卵巢刺激的患者，在人绒毛膜促性腺激素日于子宫底部水平进行横断面能量多普勒检查。将子宫内膜分为四个相等象限，并根据各象限能量多普勒的显示情况分为I级、II级、III级或IV级。当彩色多普勒信号至少到达子宫内膜基底层时，认为其为阳性。
年龄、刺激天数、直径≥16mm的卵泡数、回收的中期II卵母细胞数以及受精率在四种不同类型子宫内膜分级的患者中并无差异。四个分级的子宫内膜厚度和子宫动脉搏动指数也相似。各组间胚胎着床率也无显著差异（P = 0.53）：I级为10%；II级为11.6%；III级为15.4%；IV级为10.5%。妊娠率分别为：I级25%；II级29.7%；III级37.5%；IV级23.8%（P = 0.44）。
我们的数据表明，在ICSI程序中，单独用能量多普勒评估子宫内膜血管化并非预测妊娠的重要因素。
