Bornschein S, Hausteiner C, Zilker T, Bickel H, Förstl H
Klinik und Poliklinik für Psychiatrie und Psychotherapie, Technischen Universität München.
Nervenarzt. 2000 Sep;71(9):737-44. doi: 10.1007/s001150050658.
Multiple chemical sensitivity (MCS) or idiopathic environmental intolerance (IEI) is understood as an acquired disorder with multiple recurrent symptoms that cannot be traced to any well-known medical or psychiatric condition and is associated with diverse environmental influences that are well tolerated by the majority of people. In a prospective study, we investigated 120 consecutive patients admitted a university-based outpatient department for environmental medicine during 1 year. Apart from routine medical examination and special toxicological diagnostic procedures, a structured clinical interview for DSM-IV psychiatric disorders was performed with every patient. At least one psychiatric diagnosis was found in 100 patients. The diagnostic criteria for somatoform disorders were filled by 53 patients. We found lifetime or current affective disorders in 39 patients, anxiety disorders in 29, and substance dependency or abuse in 25. In 16 patients, personality disorders were diagnosed. Nine suffered from psychotic disorders. This is the largest prospective study with standardized psychiatric diagnostic methods concerning psychiatric morbidity and MCS. The data show that many patients with environmental health problems obviously suffer from somatoform disorders but also from other, well-known psychiatric conditions.
多重化学物质敏感症（MCS）或特发性环境不耐受症（IEI）被认为是一种后天性疾病，具有多种反复出现的症状，且无法追溯到任何已知的医学或精神疾病，它与大多数人能够良好耐受的多种环境影响因素有关。在一项前瞻性研究中，我们对一所大学附属医院环境医学门诊在1年内连续收治的120例患者进行了调查。除了常规医学检查和特殊毒理学诊断程序外，还对每位患者进行了针对《精神疾病诊断与统计手册》第四版（DSM-IV）精神疾病的结构化临床访谈。100例患者中至少发现了一种精神疾病诊断。53例患者符合躯体形式障碍的诊断标准。我们发现39例患者有终生或当前的情感障碍，29例有焦虑症，25例有物质依赖或滥用问题。16例患者被诊断为患有精神障碍。9例患有精神疾病。这是关于精神疾病发病率和多重化学物质敏感症采用标准化精神疾病诊断方法的最大规模前瞻性研究。数据表明，许多有环境健康问题的患者明显患有躯体形式障碍，同时也患有其他已知的精神疾病。
