Völker H, Siering W, Martens H
Staatliches Veterinär- und Lebensmitteluntersuchungsamt Rostock.
Berl Munch Tierarztl Wochenschr. 2000 Sep;113(9):326-30.
Time dependent changes of subclinical and clinical lameness were analysed in 493 fattening bulls in three different herds with a total number of 30,621 animals. In the majority of cases subclinical lameness were observed which were caused by metabolic acidosis or deficiencies in mineral intake (P and probably Ca). The activity of alkaline phosphatase in plasma exhibited an increase and the dry matter in bone (tubera coxae) a decrease before the appearance of clinical symptoms. Changes in bone composition were accompanied by alterations of plasma Ca and P concentrations, which finally led to clinical lameness. Hence the diagnosis was verified by simple laboratory methods as the precondition for successful treatment and prophylaxis of lameness caused by metabolic disorders.
在三个不同牛群的493头育肥牛中分析了亚临床和临床跛行随时间的变化，这三个牛群共有30,621头动物。在大多数情况下观察到亚临床跛行，其由代谢性酸中毒或矿物质摄入不足（磷以及可能的钙）引起。在临床症状出现之前，血浆中碱性磷酸酶的活性增加，而骨骼（髋结节）中的干物质减少。骨骼成分的变化伴随着血浆钙和磷浓度的改变，最终导致临床跛行。因此，通过简单的实验室方法进行诊断，作为成功治疗和预防由代谢紊乱引起的跛行的前提条件。
