Barciszewski J, Szymański M, Haertlé T
Institute of Bioorganic Chemistry of the Polish Academy of Sciences, Poznań.
J Protein Chem. 2000 May;19(4):249-54. doi: 10.1023/a:1007085627485.
Structural and functional data on 2S albumins and particularly rape seed napins are reviewed and, based on the coordinates of the three-dimensional structure of napin-like albumin BnIb, are used to model different rape napins. Surprisingly, the modeled napins, despite great sequence homology, differ in tertiary arrangements of the polypeptide chains. It is proposed that these differences in 3D structures of the analyzed rape napins may reflect their functions, which may cover many other potential beneficial purposes besides simple storage.
对2S清蛋白尤其是油菜籽napin的结构和功能数据进行了综述,并基于类napin清蛋白BnIb的三维结构坐标对不同的油菜napin进行建模。令人惊讶的是,尽管建模的napin在序列上有很大的同源性,但多肽链的三级结构排列却有所不同。有人提出,所分析的油菜napin在三维结构上的这些差异可能反映了它们的功能,除了简单的储存外,这些功能可能还涵盖许多其他潜在的有益用途。