Detection of antibody in white mice infected with Plasmodium berghei by means of the indirect immunofluorescence test.

Experiments have been conducted in order to test the efficacy of the immunofluorescence test in the detection of antibody in mice infected with Plasmodium berghei Vincke et Zips, 1948. This method enables the detection of antibody in subclinical and latent cases when an occasional parasite only is present in the blood cells. Of the various methods used for the preparation of antigen, and of the various fixatives, a satisfactory immunofluorescence reaction was obtained if unfixed erythrocytes without their plasma were used as the antigen.