非洲锥虫布氏锥虫的多态性端粒。
The polymorphic telomeres of the African Trypanosome trypanosoma brucei.
作者信息
Rudenko G
机构信息
Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3FY, UK.
出版信息
Biochem Soc Trans. 2000 Oct;28(5):536-40. doi: 10.1042/bst0280536.
Abstract
African trypanosomes have plastic genomes with extensive variability at the chromosome ends. The genes encoding the expressed major surface protein of the infective bloodstream form stages of Trypanosoma brucei and are located at telomeres. These telomeric expression-site transcription units are turning out to be surprisingly polymorphic in structure and sequence.
摘要
非洲锥虫具有可塑性基因组，其染色体末端存在广泛变异。编码布氏锥虫感染性血流形式阶段表达的主要表面蛋白的基因位于端粒处。这些端粒表达位点转录单元在结构和序列上表现出惊人的多态性。
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