De Brabander M, Borgers M
J Cell Sci. 1975 Nov;19(2):331-40. doi: 10.1242/jcs.19.2.331.
Investigations with different 'antitubulins' have shown that different cell types in culture response to prolonged treatment with the formation of annulated lamellae. These annulated lamellae are possibly derived from previously accumulated smooth endoplasmic profiles. A hypothetical explanation would be that annulated lamellae (and the nuclear membrane) are sites of tubulin synthesis or microtubular polymerization. Their appearance after induced microtubule disintegration could then be viewed upon as a reactive hyperproduction of such sites.
使用不同的“抗微管蛋白”进行的研究表明，培养中的不同细胞类型在长时间处理后会形成环形片层。这些环形片层可能源自先前积累的光滑内质网轮廓。一种假设性的解释是，环形片层（以及核膜）是微管蛋白合成或微管聚合的场所。那么在诱导微管解体后它们的出现可被视为这些场所的反应性过度产生。
