da Fonseca M A
Department of Orthodontics and Pediatric Dentistry, University of Michigan, School of Dentistry, USA.
Pediatr Dent. 2000 Sep-Oct;22(5):401-4.
Penicillin is the drug that most often leads to allergic reactions and anaphylaxis. The incidence of adverse events triggered by penicillins is believed to be between 1% and 10%. Up to one-tenth of these episodes are life-threatening, with the most serious reactions occurring in patients with no history of allergy. The case of a 5 year, 3 month-old female who had a severe allergic reaction to amoxicillin prior to a dental appointment is described. The literature on penicillin hypersensitivity is reviewed and recommendations for management of an allergic reaction in the pediatric dental office are discussed.
青霉素是最常引发过敏反应和过敏症的药物。据信，青霉素引发的不良事件发生率在1%至10%之间。这些事件中多达十分之一会危及生命，最严重的反应发生在无过敏史的患者身上。本文描述了一名5岁3个月大的女性在看牙医前对阿莫西林发生严重过敏反应的病例。对青霉素超敏反应的文献进行了综述，并讨论了儿科牙科诊所过敏反应管理的建议。
