[Antibiotic prophylaxis of infectious complications in cesarean section--prospective study].

OBJECTIVE

To verify the significance of Cefazolin administration to women who were indicated for caesarean section.

SETTING

Department of Obstetrics and Gynecology, First Faculty of Medicine, Prague, Czech republic.

METHODS

Cefazolin was administered to 30 women with a patient history risk in a dose of 1 mg i.v. after ligation of the umbilical cord. The control group consisted of 30 women. Observed parameters: weight gain during pregnancy, indications for caesarean section, culture from the cervix and vagina prior to the caesarean section, culture from the amniotic fluid, culture from the 4th day lochia, temperature curve, leucocyte count before and 4 days after the operation, complications after the surgery, administration of antibiotics, and length of hospitalisation.

RESULTS

In the group with antibiotic prophylaxis, we observed a more favourable course of the temperature curve and a smaller leucocyte count the fourth day after the surgery (p < 0.01), in comparison with the women without prophylaxis. The duration of hospitalisation in women with antibiotic prophylaxis was one day shorter and there was no occurrence of febrile complications requiring further antibiotic treatment.

CONCLUSION

Cafazolin is advantageous antibiotic for prophylaxis in caesarean section in patients with risk.