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[成人及青少年哮喘并发症自发性纵隔气肿]

[Spontaneous pneumomediastinum as a complication of asthma in adultsand adolescents].

作者信息

Lasić M, Gunek G

出版信息

Lijec Vjesn. 2000 Jul-Aug;122(7-8):168-71.

Abstract

The objective of this study was to examine the percent of spontaneous pneumomediastinums (SPM) as a complication of asthma in children and adolescent, and to examine the symptoms and clinical signs which predict SPM. A retrospective analysis was performed of patients discharged from Srebrnjak Hospital between 1988 and 1991 with the diagnoses of asthma and SPM. Ten cases (8 males and 2 females) aged 4-19 years were compared with 50 hospitalized patients. SPM was found in 4.96% of patients. Mean age of patients with SPM and asthma was 11.2 and of control patients 11.45 years. Chest pain was reported in 5/10 patients with SPM and asthma and in 0/50 of controls (p < 0.01). Subcutaneous emphysema was detected in 9/10 patients with SPM and asthma and in 0/50 of controls (p < 0.01). There was no difference in respiratory distress, partial oxygen pressure and oxygen saturation, heart rate and respiratory rate between cases and controls (p > 0.05). Systolic pressure was higher in children with SPM, but the values were within normal limits. During hospitalization in 3 patients with SPM partial left pneumothorax developed, in 1 partial bilateral pneumothorax and in 2 pneumopericardium. Subcutaneous emphysema is a significant specific clinical sign, and chest pain is a predominant symptom in the diagnosis of SPM. The patients with asthma and SPM must be treated in hospital because of potential further complication.

摘要

本研究的目的是调查儿童和青少年哮喘并发症自发性纵隔气肿(SPM)的发生率,并研究预测SPM的症状和临床体征。对1988年至1991年期间从斯雷布尔尼亚克医院出院、诊断为哮喘和SPM的患者进行回顾性分析。将10例年龄在4至19岁之间的患者(8例男性和2例女性)与50例住院患者进行比较。发现SPM在4.96%的患者中出现。患有SPM和哮喘的患者平均年龄为11.2岁,对照患者为11.45岁。10例患有SPM和哮喘的患者中有5例报告胸痛,而50例对照患者中无1例报告胸痛(p<0.01)。10例患有SPM和哮喘的患者中有9例检测到皮下气肿,而50例对照患者中无1例检测到皮下气肿(p<0.01)。病例组和对照组在呼吸窘迫、部分氧分压和氧饱和度、心率和呼吸频率方面无差异(p>0.05)。患有SPM的儿童收缩压较高,但数值在正常范围内。在住院期间,3例患有SPM的患者出现部分左侧气胸,1例出现部分双侧气胸,2例出现心包积气。皮下气肿是一个重要的特异性临床体症,胸痛是SPM诊断中的主要症状。由于可能出现进一步并发症,患有哮喘和SPM的患者必须住院治疗。

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