Kalichman S C, Rompa D, Cage M
Center for AIDS Intervention Research, Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee 53226, USA.
J Nerv Ment Dis. 2000 Oct;188(10):662-70. doi: 10.1097/00005053-200010000-00004.
HIV-AIDS is a prevalent medical diagnosis in U.S. cities, and symptoms of depression are common in persons with HIV infection. This study examined the effects of overlapping symptoms of HIV disease and somatic depression that can inflate scores on the Beck Depression Inventory (BDI) and the Centers for Epidemiological Studies Depression Scale (CESD). Results from 357 HIV positive men and women identified discrete subsets of depression symptoms that correspond with symptoms of HIV infection. Removing somatic subsets of depression symptoms improved the clinical utility of the BDI and CESD. Clearer symptom separation occurred with the BDI than the CESD, but the CESD may be more sensitive than the BDI to depression associated with progression of HIV disease. Findings suggest that depression scales that include somatic symptoms will inflate depression scores in people living with HIV infection, and available methods for distinguishing overlapping symptoms should be employed when assessing people living with HIV infection.
艾滋病在美国城市是一种常见的医学诊断，抑郁症症状在艾滋病毒感染者中很常见。本研究考察了艾滋病相关症状与躯体性抑郁的重叠症状对贝克抑郁量表（BDI）和流行病学研究中心抑郁量表（CESD）得分的影响，这些重叠症状会使得分虚高。对357名艾滋病毒呈阳性的男性和女性的研究结果确定了与艾滋病毒感染症状相对应的不同抑郁症状子集。去除抑郁症状的躯体性子集提高了BDI和CESD的临床实用性。BDI比CESD能更清晰地分离症状，但CESD可能比BDI对与艾滋病毒疾病进展相关的抑郁更敏感。研究结果表明，包含躯体症状的抑郁量表会使艾滋病毒感染者的抑郁得分虚高，在评估艾滋病毒感染者时应采用现有的区分重叠症状的方法。
