亚甲蓝诱发新生儿葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症患者出现高胆红素血症。
Methylene blue-induced hyperbilirubinemia in neonatal glucose-6-phosphate dehydrogenase (G6PD) deficiency.
作者信息
Gauthier T W
机构信息
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
出版信息
J Matern Fetal Med. 2000 Jul-Aug;9(4):252-4. doi: 10.1002/1520-6661(200007/08)9:4<252::AID-MFM14>3.0.CO;2-U.
Abstract
Methylene blue continues to be used in the gravid female. We report three premature neonates exposed to methylene blue that experienced severe hemolytic reactions requiring exchange transfusions. Two neonates were subsequently diagnosed with G6PD deficiency. Continued caution is warranted prior to the use of methylene blue in the gravid female.
摘要
亚甲蓝仍用于妊娠女性。我们报告了3例暴露于亚甲蓝的早产新生儿，他们经历了严重的溶血反应，需要进行换血治疗。随后，两名新生儿被诊断为葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症。在妊娠女性中使用亚甲蓝之前，仍需谨慎。
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