• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

亚甲蓝诱发新生儿葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症患者出现高胆红素血症。

Methylene blue-induced hyperbilirubinemia in neonatal glucose-6-phosphate dehydrogenase (G6PD) deficiency.

作者信息

Gauthier T W

机构信息

Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

出版信息

J Matern Fetal Med. 2000 Jul-Aug;9(4):252-4. doi: 10.1002/1520-6661(200007/08)9:4<252::AID-MFM14>3.0.CO;2-U.

DOI:10.1002/1520-6661(200007/08)9:4<252::AID-MFM14>3.0.CO;2-U
PMID:11048840
Abstract

Methylene blue continues to be used in the gravid female. We report three premature neonates exposed to methylene blue that experienced severe hemolytic reactions requiring exchange transfusions. Two neonates were subsequently diagnosed with G6PD deficiency. Continued caution is warranted prior to the use of methylene blue in the gravid female.

摘要

亚甲蓝仍用于妊娠女性。我们报告了3例暴露于亚甲蓝的早产新生儿，他们经历了严重的溶血反应，需要进行换血治疗。随后，两名新生儿被诊断为葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症。在妊娠女性中使用亚甲蓝之前，仍需谨慎。

相似文献

1
Methylene blue-induced hyperbilirubinemia in neonatal glucose-6-phosphate dehydrogenase (G6PD) deficiency.亚甲蓝诱发新生儿葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症患者出现高胆红素血症。
J Matern Fetal Med. 2000 Jul-Aug;9(4):252-4. doi: 10.1002/1520-6661(200007/08)9:4<252::AID-MFM14>3.0.CO;2-U.
2
Untoward neonatal effect of intraamniotic administration of methylene blue.羊膜腔内注射亚甲蓝对新生儿的不良影响。
Obstet Gynecol. 1976 Jul;48(1 Suppl):74S-75S.
3
Hemolytic anemia after methylene blue therapy for aniline-induced methemoglobinemia.亚甲蓝治疗苯胺所致高铁血红蛋白血症后发生的溶血性贫血。
Vet Hum Toxicol. 2002 Feb;44(1):19-21.
4
Methylene-blue-induced hyperbilirubinemia and phototoxicity in a neonate.亚甲蓝诱发新生儿高胆红素血症及光毒性反应
Clin Pediatr (Phila). 2000 Nov;39(11):659-61. doi: 10.1177/000992280003901106.
5
Unfavorable neonatal outcome after intraamniotic injection of methylene blue.羊膜腔内注射亚甲蓝后不良的新生儿结局。
Obstet Gynecol. 1983 Mar;61(3 Suppl):35S-37S.
6
Methylene blue-induced phototoxicity: an unrecognized complication.亚甲蓝诱导的光毒性：一种未被认识到的并发症。
Pediatrics. 1996 May;97(5):717-21.
7
Donor blood glucose 6-phosphate dehydrogenase deficiency reduces the efficacy of exchange transfusion in neonatal hyperbilirubinemia.供体葡萄糖-6-磷酸脱氢酶缺乏会降低新生儿高胆红素血症换血疗法的疗效。
Pediatrics. 2009 Jan;123(1):e96-e100. doi: 10.1542/peds.2008-2021. Epub 2008 Dec 22.
8
Neonatal complications.新生儿并发症。
Obstet Gynecol. 1973 Mar;41(3):476-7.
9
Hemolytic anemia and methemoglobinemia in a preterm baby as a complication of antenatal intraamnial injection of toluidine blue.
Klin Padiatr. 2013 Sep;225(5):263-5. doi: 10.1055/s-0033-1333756. Epub 2013 Mar 21.
10
An update on the prevalence of glucose-6-phosphate dehydrogenase deficiency and neonatal jaundice in Tehran neonates.德黑兰新生儿葡萄糖-6-磷酸脱氢酶缺乏症和新生儿黄疸患病率的最新情况。
Clin Biochem. 2004 Mar;37(3):241-4. doi: 10.1016/j.clinbiochem.2003.11.010.

引用本文的文献

1
Efficacy and safety of methylene blue in the treatment of malaria: a systematic review.甲烯蓝治疗疟疾的疗效和安全性：系统评价。
BMC Med. 2018 Apr 25;16(1):59. doi: 10.1186/s12916-018-1045-3.
2
G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications.葡萄糖-6-磷酸脱氢酶缺乏症：一个具有持续临床意义的经典药物遗传学范例。
Br J Haematol. 2014 Feb;164(4):469-80. doi: 10.1111/bjh.12665. Epub 2013 Dec 28.
3
PharmGKB summary: methylene blue pathway.药物基因组学知识库总结：亚甲蓝途径。
Pharmacogenet Genomics. 2013 Sep;23(9):498-508. doi: 10.1097/FPC.0b013e32836498f4.
4
Medications and glucose-6-phosphate dehydrogenase deficiency: an evidence-based review.药物与葡萄糖-6-磷酸脱氢酶缺乏：循证综述。
Drug Saf. 2010 Sep 1;33(9):713-26. doi: 10.2165/11536520-000000000-00000.
5
Is there a need for neonatal screening of glucose-6-phosphate dehydrogenase deficiency in Canada?加拿大是否有必要对葡萄糖-6-磷酸脱氢酶缺乏症进行新生儿筛查？
Mcgill J Med. 2007 Jan;10(1):31-4.