Correa L, Pittet D
Infection Control Programme, Department of Internal Medicine, University of Geneva Hospitals, Geneva, Switzerland.
J Hosp Infect. 2000 Oct;46(2):89-95. doi: 10.1053/jhin.2000.0803.
Despite infection control efforts, bacteraemia remains one of the most frequent and challenging hospital-acquired infections and is associated with high attributable morbidity and mortality and additional use of healthcare resources. Prevention and control of hospital-acquired blood-stream infection requires improved detection methods, better definition of patient populations at risk, more refined guidelines for the interpretation of positive blood cultures and a better discrimination between sporadic contaminants and true bacteraemia. These issues are addressed in the current review together with those related to the diagnosis, management and recent advances in the prevention of cathether-related bacteraemia, the leading cause of hospital-acquired blood-stream infection. Finally, the reasons and perspectives for blood-stream infection surveillance are briefly discussed.
尽管采取了感染控制措施，但菌血症仍然是最常见且最具挑战性的医院获得性感染之一，与高发病率、高死亡率以及额外的医疗资源使用相关。预防和控制医院获得性血流感染需要改进检测方法、更好地界定高危患者群体、制定更完善的血培养阳性结果解读指南，以及更准确地区分散发性污染物与真正的菌血症。本综述将探讨这些问题，以及与导管相关菌血症（医院获得性血流感染的主要原因）的诊断、管理和预防方面的最新进展。最后，简要讨论血流感染监测的原因和前景。
