Gunasekaran Santosh, Mahadevaiah Sumana
JSS Medical College, Mysuru, Karnataka, India.
Department of Microbiology, JSS Medical College, Mysuru, Karnataka, India.
Indian J Crit Care Med. 2020 Apr;24(4):252-257. doi: 10.5005/jp-journals-10071-23384.
To compare the predicted vs observed mortality rate, criticality, and length of stay of the patients with healthcare-associated infections (HAIs) in intensive care units (ICUs) of a tertiary health center through acute physiology and chronic health evaluation (APACHE) IV scoring. To analyze the drug sensitivity pattern of the isolated pathogen.
This is a prospective observational study involving the patients admitted to various ICUs of a tertiary care teaching hospital. Among 1,229 patients who were admitted in the ICUs for a period of 2.5 months (74 days), 767 patients stayed beyond 48 hours. They were monitored and 87 of them who developed HAIs were included in the study. The organisms isolated from the infection site were identified, and the drug resistance pattern was reported as per standard guidelines. The patients were followed up till their discharge, and adequate details pertaining to the study were collected including demographic details and physiological and biochemical parameters to calculate APACHE IV score, length of stay, and prognosis.
Intensive care units of JSS Hospital, Mysuru, Karnataka, India.
SUBJECTS/PATIENTS: All patients who developed HAI in ICUs.
Nil.
The HAI rate observed in this study was 15.7%. Ventilator-associated pneumonia (VAP) was the most common type of infection. and were the frequently isolated organisms. There was a high prevalence of drug resistance among these pathogens. The ICU mortality in infected patients was 21.83%, roughly twice as that of uninfected patients. The observed length of stay was 11.66 (±8.53) days.
Healthcare-associated infection was associated with long duration of ICU stay. There was a high prevalence of drug resistance to various antibiotics. Acute physiology and chronic health evaluation IV score was not found to be good scoring system to predict the mortality and length of stay in the patients who had HAI.
Gunasekaran S, Mahadevaiah S. Healthcare-associated Infection in Intensive Care Units: Overall Analysis of Patient Criticality by Acute Physiology and Chronic Health Evaluation IV Scoring and Pathogenic Characteristics. Indian J Crit Care Med 2020;24(4):252-257.
通过急性生理学与慢性健康状况评价（APACHE）IV评分，比较某三级医疗中心重症监护病房（ICU）中发生医疗相关感染（HAI）患者的预测死亡率与观察到的死亡率、病情严重程度及住院时间。分析分离出的病原体的药敏模式。
这是一项前瞻性观察性研究，涉及一所三级护理教学医院各ICU收治的患者。在1229名入住ICU达2.5个月（74天）的患者中，767名患者住院时间超过48小时。对他们进行监测，其中87名发生HAI的患者被纳入研究。从感染部位分离出的微生物进行鉴定，并按照标准指南报告耐药模式。对患者进行随访直至出院，收集与研究相关的充分细节，包括人口统计学细节以及生理和生化参数，以计算APACHE IV评分、住院时间和预后。
印度卡纳塔克邦迈索尔市JSS医院的重症监护病房。
研究对象/患者：所有在ICU发生HAI的患者。
无。
本研究中观察到的HAI发生率为15.7%。呼吸机相关性肺炎（VAP）是最常见的感染类型。[此处原文缺失两种常见分离菌的具体信息]是最常分离出的微生物。这些病原体中耐药情况普遍。感染患者的ICU死亡率为21.83%，约为未感染患者的两倍。观察到的住院时间为11.66（±8.53）天。
医疗相关感染与ICU住院时间延长有关。对各种抗生素的耐药情况普遍。未发现急性生理学与慢性健康状况评价IV评分是预测发生HAI患者死亡率和住院时间的良好评分系统。
Gunasekaran S, Mahadevaiah S. 重症监护病房中的医疗相关感染：通过急性生理学与慢性健康状况评价IV评分及致病特征对患者病情严重程度的总体分析。《印度重症监护医学杂志》2020年；24(4):252 - 257。
