Sansom L N, O'Reilly W J, Wiseman C W, Stern L M, Derham J
Med J Aust. 1975 Oct 11;2(15):593-5.
A cross-over study was conducted to compare the plasma phenytoin levels produced by different phenytoin preparations available in Australia. The preparations were found not to be equivalent, a liquid suspension product producing higher levels compared with capsule and tablet formulations. The clinical significance and possible explantation are discussed.
进行了一项交叉研究，以比较澳大利亚市面上不同苯妥英制剂所产生的血浆苯妥英水平。结果发现这些制剂并不等效，一种液体悬浮剂产品产生的水平高于胶囊和片剂剂型。讨论了其临床意义及可能的解释。
