Janik J E, Bloch C A, Janik J S
Department of Pediatric Surgery, The Children's Hospital, University of Colorado Health Sciences Center, Denver, USA.
J Pediatr Surg. 2000 Oct;35(10):1517-9. doi: 10.1053/jpsu.2000.16430.
Neonatal hyperparathyroidism (NPHP) is exceedingly rare and often fatal. A neonate is presented with a serum calcium concentration of 33 mg/dL, an intrathyroid parathyroid gland, and a family history of hypocalciuric hypercalcemia (FHH). She underwent successful total parathyroidectomy. Six years later, the child is normocalcemic and developmentally normal, requiring calcium and calcitrol replacement. The results of this case support the concept that NPHP is associated with parathyroid hyperplasia and is part of a continuum that includes FHH.
新生儿甲状旁腺功能亢进症（NPHP）极为罕见，且往往致命。一名新生儿血清钙浓度为33mg/dL，甲状腺内有甲状旁腺，并有家族性低钙血症性高钙血症（FHH）病史。她接受了成功的甲状旁腺全切除术。六年后，该患儿血钙正常，发育正常，需要补充钙和骨化三醇。该病例结果支持以下观点：NPHP与甲状旁腺增生有关，是包括FHH在内的连续病症的一部分。
